- Demand perfection with NYX Professional Makeup Matte Setting Spray, theÃ‚Â #1 setting spray in America*! Makeup lovers and professionals alike knowÃ‚Â NYX Professional Makeup Matte Setting SprayÃ‚Â is the key to fresh, matte makeup that lasts. Our must-have, lightweight makeup setting spray has a gorgeous matte finish, in a formula that is comfortable, breathable, and long-lasting. Our best-selling Matte Setting Spray works hard to make sure your makeup stays put all day (and into the night). All you need to do is shake, spray, and set.